Osteoimmunology: entwined regulation of integrated systems
نویسندگان
چکیده
منابع مشابه
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متن کاملOsteoimmunology: interactions of the immune and skeletal systems.
Bone is a dynamic tissue that provides mechanical support, physical protection, and enables movement. Bone also serves as a storage site for minerals and is where blood cells are produced. Bone homeostasis is regulated by the balance between bone formation and resorption, and involves the coordinated action of osteoblasts and osteoclasts. Osteoblasts are bone-forming cells that secrete organic ...
متن کاملOsteoimmunology and osteoporosis
The concept of osteoimmunology is based on growing insight into the links between the immune system and bone at the anatomical, vascular, cellular, and molecular levels. In both rheumatoid arthritis (RA) and ankylosing spondylitis (AS), bone is a target of inflammation. Activated immune cells at sites of inflammation produce a wide spectrum of cytokines in favor of increased bone resorption in ...
متن کاملOsteoimmunology and Beyond
OBJECTIVE Osteoimmunology investigates interactions between skeleton and immune system. In the light of recent discoveries in this field, a new reading register of osteoporosis is actually emerging, in which bone and immune cells are strictly interconnected. Osteoporosis could therefore be considered a chronic immune mediated disease which shares with other age related disorders a common inflam...
متن کاملOsteoimmunology and nutritional science.
The concept of osteoimmunology was established more than a decade ago and is based on the reciprocal relationship between immune and bone cells. This way of looking to these two organs skeletal and immune system, has resulted in the development of clinical therapeutics for seemingly disparate but linked by the common themes of inflammation and bone remodeling. 1 Osteoimmunology includes osteopo...
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ژورنال
عنوان ژورنال: Seminars in Immunopathology
سال: 2019
ISSN: 1863-2297,1863-2300
DOI: 10.1007/s00281-019-00763-2